Trimethoprim Glutamate

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SHANDONG FUMEILE ANIMALS PHARMACEUTICAL CO.,LTD

Business Type:Manufacturer

Country/Region:China

Ddu Verified

HOT Rank

8/10

Product Information

  • Transport Package:25kgs/drum
  • Specification:in-house
  • Trademark:FUMEILE
  • Country of Origin:CHINA

Description

                        Trimethoprim Glutamate

 

This product is combined by glutamic acid and trimethoprim ,molecular formula is C14H18N4O3•C5H9NO4.it contains not less than 98%C14H18N4O3•C5H9NO4 the dried.

[Characters] 

This product is white to slightly yellow crystalline powder, odorless. This product is soluble in water, slightly soluble in ethanol or acetic acid.

[Melting Point]  Its melting point is from 217 to 221℃.

[Identification]

(1) Add this product 30mg into 2ml of water,after dissolved,add iodine test solution 2 drops, a dark brown precipitate is produced.

(2) Take this product 30mg, precisely weighed then add water 10ml, precisely

measure 1ml of this solution ,diluted with water into a solution containing 1 ml per 30 μg. According to UV visible spectrophotometry (Appendix 0401), the solution has the greatest absorption at the 287nm wave strengths.

    (3) Dissolve about 30mg of  this product into 2ml water , add a few drops of ninhydrin solution and heated it ,the solution becomes blue to violet.

[Test]

[Acidity]

Add 0.5 g of this product into 30 ml of water, shake it to dissolved, pH should be 4.5 ~ 6.5.

[Clarity and Color]

Dissolve 0.5 g of the sample by 30 ml water , the solution should be clear.

[Loss of Drying]

Dry this product at 105 degrees to a constant weight, the loss should be less than 3.0%.

[Ignition Residue] Should be less than 0.1%.

[Assay]

Add 0.3g of this produt into 20ml of glacial acetic acid,heat the solution to dissolved, add one drop of crystal violet indicator after chills down.Add the perchloric acid titrant(0.1mol/L) until the solution becomes blue and correct the result by bank test. Every 1 ml of the perchloric acid titrant (0.1mol/l) amounts to 21.9 mg of C14H18N4O3•C5H9NO4.

[Category] Antibacterial synergist.

[Storage]  Shaded and Sealed storage.

 

 

 

 

                                                                              SHANDONG FUMEILE ANIMAL PHARMACEUTICALS CO.,LTD.

                                                                              TEL: +86-

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